FDA: Biotin interference still concerning, particularly with Troponin tests


Biotin (vitamin B7), a water-soluble vitamin, is often found in multivitamins, prenatal vitamins, and dietary supplements. As many lab tests use biotin technology due its ability to bond with specific proteins, ingesting high levels of biotin can cause clinically significant incorrect lab results.

The Food and Drug Administration (FDA) has issued an updated safety communication reminding healthcare professionals about the possibility of biotin interference with certain lab tests.

Specifically, the Agency is concerned with reports of biotin interference causing falsely low cardiac troponin levels that could potentially lead to a missed diagnosis.

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