117 - Cardiovascular markers: what does it change in the routine daily care of patients with new “gold standard”?
Autor(s): M. Cassin, D. Rubin
Issue: RIMeL - IJLaM, Vol. 4, N. 3-S1, 2008 (MAF Servizi srl ed.)
Page(s): 117
In the past years WHO defined myocardial infarction from symptoms, ECG abnormalities, and enzymes. However, the development of more sensitive and specific biomarkers allows detection of ever smaller amounts of myocardial necrosis. Accordingly it requires a more precise definition of myocardial infarction. In response to this issue ESC and ACC in 2000 re-examined the definition of myocardial infarction, with recent update (2007) by ESC, AHA, WHF in order to refine the ESC/ACC criteria for the diagnosis of myocardial infarction from various perspectives. The term of myocardial infarction should now be used when there is evidence of myocardial necrosis in a clinical setting consistent with myocardial ischemia. Under these conditions, from biochemical point of view, there must be detection of rise and fall of biomarkers, preferably troponin, with at least one value above the 99th percentile of the upper reference limit, together with evidence of myocardial ischemia. ....