Don't miss the upcoming ISLH November Webinar!
06/11/2023
On Thursday, November 16th, 2023 the International Society for Laboratory Hematology will host the next webinar in the e-Learning series: "Diagnosis of Acquired Thrombotic Thrombocytopenic Purpura".
The webinar will be held by Katrien Devreese, MD, PhD, Professor in Hematology/Coagulation at Ghent University, Belgium, Head of the Coagulation Laboratory Ghent University Hospital, Belgium.
Overview: Thrombotic thrombocytopenic purpura (TTP) is a rare and life-threatening thrombotic microangiopathy characterized by microangiopathic hemolytic anemia, severe thrombocytopenia, and organ ischemia linked to disseminated microthrombi.
TTP is specifically related to a severe deficiency in ADAMTS13, the von Willebrand factor-cleaving protease. ADAMTS13 deficiency is most frequently acquired via ADAMTS13 autoantibodies, but rarely, it is inherited via mutations of the ADAMTS13 gene.
Diagnosis relies on the combination of the clinical symptoms, the disturbed laboratory parameters and the measurement of ADAMTS13.
Prompt identification/exclusion of TTP can be facilitated by rapid ADAMTS13 testing. A number of diagnostic assays are available to identify ADAMTS 13 activity, with different measurement techniques and different turn- around-time. Antibodies to ADAMTS 13 must be measured to differentiate between the immune mediated TTP and the inherited form. ADAMTS13 activity monitoring in long-term follow-up of patients with TTP is crucial to identify relapses.
Learning Objectives:
- Understand the pathophysiology of Thrombotic Thrombocytopenic Purpura (TTP)
- Understand the importance of the need of ADAMTS13 activity testing to identify/exclude TTP
- Have knowledge of the different tests for ADAMTS13 activity and autoantibody measurement
All webinars will begin promptly at 11:00 AM Eastern Time US and are approximately 50 minutes long. There is no charge to participate in the live webinar.
We look forward to your participation in this event!
Notizie collegate
