236 - Legal-medicine application of CDT index. Data work about Brescia’s population.

Background. Carbohydrate-deficient transferrin (CDT) is considered a biochemical marker with diagnostic sensitivity and specificity for regular high alcohol intake. The aim of the present work was the comparison between CDT index in males and CDT index in females. Methods. Serum samples from 110 subjects with different alcohol consumption, declared in anonymous questionnaire, have been analyzed with HPLC/UV with validated method using commercial kit ClinRep® Recipe for determination of CDT. Results and conclusions. The variables analyzed have been correlated and reported in graphics; the means of CDT’s population was 0,68%, con S.D. 0,291, variance 0,08, median 0,65, VC 42,78; the CDT’s mean has resulted 0,65% in males and 0,79% in females. The females in this study have a major CDT than the males. The correlations between CDT, ALT, age, weight and the knowledge of the real alcohol intake confirms the utility of the CDT index to discrimination abuse from moderate use of alcohol.