247 - L’Ematologia di Laboratorio

P. Cappelletti - Serie di Ematologia di Laboratorio - a cura del GdS-E SIMeL The Laboratory Hematology Since its birth, the Hematology is both a laboratory (morphologic and technologic) and clinical discipline. During the second half of the past century, the hematology laboratory has become a world remote from the clinician, because of both technical progress, i.e. the flow-cytometry, and remarkable scientific advances, especially the genetic and molecular revolution. Thus, the concept of Laboratory Hematology is challenged. Nevertheless, the continue role of the optical and “cytometric” morphology in case-finding and diagnosis, the need of integration of all available information, including genetic, immunophenotypic, biologic, clinical and morphologic features for the classification of hematopoietic and lymphoid neoplasm, the growing importance of the laboratory measurements in the so-called “nonhematological hematology”, support the idea of an actual laboratory hematology diagnostic logic. It is based on solid medical and technologic knowledge, on the integration of the diagnostic information by different tools, on a correct and effective process of validation and interpretation of the findings, on an “expressive” results for the effectiveness of the clinical action, and on a two-ways communication with the clinicians for an appropriate and efficient use of the Hematology Laboratory.